471.0K XNAS Volume
XNAS 19 Mar, 2025 12:28 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Christopher Hite | EVP & Vice Chairman | 14 Feb 2025 | 300,000 | 600,000 | - | 0 | Class A Ordinary Shares | ||
| Christopher Hite | EVP & Vice Chairman | 14 Feb 2025 | 30,000 | 86,641 | - | - | LP interests in RPI US Partners 2019, LP | ||
| Henry A. Fernandez | Director | Grant, award, or other acquisition of securities at price $ 24.94 per share. | 31 Dec 2024 | 1,503 | 55,505 | - | 24.9 | 37,487 | Class A Ordinary Shares |
| Bonnie L. Bassler | Director | Grant, award, or other acquisition of securities at price $ 24.94 per share. | 31 Dec 2024 | 1,503 | 61,299 | - | 24.9 | 37,487 | Class A Ordinary Shares |
| Henry A. Fernandez | Director | Grant, award, or other acquisition of securities at price $ 27.92 per share. | 30 Sep 2024 | 1,342 | 54,002 | - | 27.9 | 37,475 | Class A Ordinary Shares |
| Bonnie L. Bassler | Director | Grant, award, or other acquisition of securities at price $ 27.92 per share. | 30 Sep 2024 | 1,342 | 59,796 | - | 27.9 | 37,475 | Class A Ordinary Shares |
| Terrance Coyne | EVP & CFO | Gift of securities by or to the insider at price $ 0.00 per share. | 12 Aug 2024 | 2,000 | 44,350 | - | - | ICAI Interests | |
| George Lloyd | EVP, Investments & CLO | Gift of securities by or to the insider at price $ 0.00 per share. | 12 Aug 2024 | 7,920 | 0 | - | - | LP interests in RPI US Partners 2019, LP | |
| Marshall Urist | EVP, Research & Investments | Gift of securities by or to the insider at price $ 0.00 per share. | 12 Aug 2024 | 2,182 | 126,412 | - | - | LP interests in RPI US Partners 2019, LP | |
| Henry A. Fernandez | Director | Grant, award, or other acquisition of securities at price $ 26.80 per share. | 28 Jun 2024 | 1,399 | 52,660 | - | 26.8 | 37,493 | Class A Ordinary Shares |
| Bonnie L. Bassler | Director | Grant, award, or other acquisition of securities at price $ 26.80 per share. | 28 Jun 2024 | 1,399 | 58,454 | - | 26.8 | 37,493 | Class A Ordinary Shares |
| David C. Hodgson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2024 | 9,293 | 25,714 | - | 0 | Class A Ordinary Shares | |
| Henry A. Fernandez | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2024 | 9,293 | 51,261 | - | 0 | Class A Ordinary Shares | |
| Gregory Norden | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2024 | 9,293 | 73,738 | - | 0 | Class A Ordinary Shares | |
| Ted W. Love | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2024 | 9,293 | 46,234 | - | 0 | Class A Ordinary Shares | |
| Bonnie L. Bassler | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2024 | 9,293 | 57,055 | - | 0 | Class A Ordinary Shares | |
| Catherine M. Engelbert | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 07 Jun 2024 | 9,293 | 43,514 | - | 0 | Class A Ordinary Shares | |
| Christopher Hite | EVP & Vice Chairman | 13 May 2024 | 30,000 | 541 | - | - | LP interests in RPI US Partners 2019, LP | ||
| Christopher Hite | EVP & Vice Chairman | 13 May 2024 | 300,000 | 370,000 | - | 0 | Class A Ordinary Shares | ||
| Henry A. Fernandez | Director | Grant, award, or other acquisition of securities at price $ 30.23 per share. | 28 Mar 2024 | 1,240 | 41,968 | - | 30.2 | 37,483 | Class A Ordinary Shares |
| Bonnie L. Bassler | Director | Grant, award, or other acquisition of securities at price $ 30.23 per share. | 28 Mar 2024 | 1,240 | 47,762 | - | 30.2 | 37,483 | Class A Ordinary Shares |
| B. Riggs Rory | Director | 20 Feb 2024 | 300,000 | 320,099 | - | 0 | Class A Ordinary Shares | ||
| Rory Riggs B. | Director | 20 Feb 2024 | 30,000 | 270,000 | - | - | LP interests in RPI US Partners 2019, LP | ||
| Riggs B. Rory | Director | Sale of securities on an exchange or to another person at price $ 27.55 per share. | 02 Jan 2024 | 35,702 | 20,099 | - | 27.5 | 983,504 | Class A Ordinary Shares |
| Riggs B. Rory | Director | Sale of securities on an exchange or to another person at price $ 27.79 per share. | 02 Jan 2024 | 199,098 | 55,801 | - | 27.8 | 5,532,276 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 28.52 per share. | 02 Jan 2024 | 235,200 | 254,899 | - | 28.5 | 6,707,081 | Class A Ordinary Shares |
| L. Bonnie Bassler | Director | Grant, award, or other acquisition of securities at price $ 27.71 per share. | 29 Dec 2023 | 1,353 | 46,522 | - | 27.7 | 37,493 | Class A Ordinary Shares |
| A. Fernandez Henry | Director | Grant, award, or other acquisition of securities at price $ 27.71 per share. | 29 Dec 2023 | 1,353 | 40,728 | - | 27.7 | 37,493 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 08 Aug 2023 | 6,500 | 347,559 | - | - | LP interests in RPI US Partners 2019, LP | |
| Terrance Coyne | EVP & CFO | Gift of securities by or to the insider at price $ 0.00 per share. | 08 Aug 2023 | 1,650 | 46,350 | - | - | ICAI Interests | |
| George Lloyd | EVP, Investments & CLO | Gift of securities by or to the insider at price $ 0.00 per share. | 08 Aug 2023 | 5,555 | 0 | - | - | LP interests in RPI US Partners 2019, LP | |
| Terrance Coyne | EVP & CFO | Sale of securities on an exchange or to another person at price $ 30.93 per share. | 12 Jul 2023 | 37,500 | 865,000 | - | 30.9 | 1,159,958 | Class A Ordinary Shares |
| Terrance Coyne | EVP & CFO | Sale of securities on an exchange or to another person at price $ 31.07 per share. | 12 Jul 2023 | 37,500 | 902,500 | - | 31.1 | 1,165,256 | Class A Ordinary Shares |
| Henry A. Fernandez | Director | Grant, award, or other acquisition of securities at price $ 31.03 per share. | 30 Jun 2023 | 1,208 | 37,991 | - | 31.0 | 37,481 | Class A Ordinary Shares |
| Bonnie L. Bassler | Director | Grant, award, or other acquisition of securities at price $ 31.03 per share. | 30 Jun 2023 | 1,208 | 43,785 | - | 31.0 | 37,481 | Class A Ordinary Shares |
| Pablo Legorreta | Director, CEO, Chairman of the Board, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 29.51 per share. | 28 Jun 2023 | 130,000 | 600,000 | - | 29.5 | 3,836,768 | Class A ordinary shares |
| David C. Hodgson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jun 2023 | 7,747 | 16,421 | - | 0 | Class A Ordinary Shares | |
| Henry A. Fernandez | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jun 2023 | 7,747 | 36,783 | - | 0 | Class A Ordinary Shares | |
| Gregory Norden | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jun 2023 | 7,747 | 64,445 | - | 0 | Class A Ordinary Shares | |
| Ted W. Love | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jun 2023 | 7,747 | 36,941 | - | 0 | Class A Ordinary Shares | |
| Rory B. Riggs | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jun 2023 | 7,747 | 14,509 | - | 0 | Class A Ordinary Shares | |
| Bonnie L. Bassler | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jun 2023 | 7,747 | 42,577 | - | 0 | Class A Ordinary Shares | |
| Catherine M. Engelbert | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jun 2023 | 7,747 | 33,211 | - | 0 | Class A Ordinary Shares | |
| M. Germano Giuliani | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Jun 2023 | 7,747 | 7,747 | - | 0 | Class A Ordinary Shares | |
| Pablo Legorreta | Director, CEO, Chairman of the Board, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 33.00 per share. | 12 Jun 2023 | 45,000 | 425,000 | - | 33.0 | 1,484,946 | Class A ordinary shares |
| Pablo Legorreta | Director, CEO, Chairman of the Board, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 32.78 per share. | 12 Jun 2023 | 45,000 | 470,000 | - | 32.8 | 1,474,902 | Class A ordinary shares |
| George Lloyd | EVP, Investments & CLO | Sale of securities on an exchange or to another person at price $ 33.54 per share. | 02 Jun 2023 | 19,215 | 109,099 | - | 33.5 | 644,446 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & CLO | Sale of securities on an exchange or to another person at price $ 33.65 per share. | 02 Jun 2023 | 92,221 | 120,000 | - | 33.6 | 3,102,803 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & CLO | Sale of securities on an exchange or to another person at price $ 33.54 per share. | 02 Jun 2023 | 1,686 | 128,314 | - | 33.5 | 56,542 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & CLO | Sale of securities on an exchange or to another person at price $ 33.82 per share. | 02 Jun 2023 | 79,099 | 30,000 | - | 33.8 | 2,674,796 | Class A Ordinary Shares |
| Pablo Legorreta | Director, CEO, Chairman of the Board, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 32.25 per share. | 24 May 2023 | 150,000 | 380,000 | - | 32.2 | 4,837,440 | Class A ordinary shares |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 32.82 per share. | 22 May 2023 | 1,750,000 | 6,762 | - | 32.8 | 57,435,000 | Class A Ordinary Shares |
| Pablo Legorreta | Director, CEO, Chairman of the Board, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 33.57 per share. | 16 May 2023 | 160,388 | 160,388 | - | 33.6 | 5,383,728 | Class A ordinary shares |
| Pablo Legorreta | Director, CEO, Chairman of the Board, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 32.94 per share. | 16 May 2023 | 69,612 | 230,000 | - | 32.9 | 2,293,096 | Class A ordinary shares |
| Pablo Legorreta | Director, CEO, Chairman of the Board, Ten Percent Owner | Gift of securities by or to the insider at price $ 0.00 per share. | 12 May 2023 | 10,269 | 0 | - | - | ICAI Interests | |
| Pablo Legorreta | Director, CEO, Chairman of the Board, Ten Percent Owner | Gift of securities by or to the insider at price $ 0.00 per share. | 12 May 2023 | 10,269 | 692,701 | - | - | ICAI Interests | |
| Rory B. Riggs | Director | 09 May 2023 | 30,000 | 354,059 | - | - | LP interests in RPI US Partners 2019, LP | ||
| Rory B. Riggs | Director | 09 May 2023 | 300,000 | 1,756,762 | - | 0 | Class A Ordinary Shares | ||
| Henry A. Fernandez | Director | Grant, award, or other acquisition of securities at price $ 35.73 per share. | 31 Mar 2023 | 1,049 | 29,036 | - | 35.7 | 37,478 | Class A Ordinary Shares |
| Bonnie L. Bassler | Director | Grant, award, or other acquisition of securities at price $ 35.73 per share. | 31 Mar 2023 | 1,049 | 34,830 | - | 35.7 | 37,478 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 36.26 per share. | 29 Mar 2023 | 130,024 | 1,456,762 | - | 36.3 | 4,714,345 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 36.95 per share. | 29 Mar 2023 | 9,926 | 1,586,786 | - | 37.0 | 366,766 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & CLO | Sale of securities on an exchange or to another person at price $ 37.03 per share. | 28 Mar 2023 | 12,779 | 212,221 | - | 37.0 | 473,165 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & CLO | Sale of securities on an exchange or to another person at price $ 37.06 per share. | 28 Mar 2023 | 100,000 | 225,000 | - | 37.1 | 3,706,130 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & CLO | Sale of securities on an exchange or to another person at price $ 37.27 per share. | 23 Feb 2023 | 25,000 | 325,000 | - | 37.3 | 931,658 | Class A Ordinary Shares |
| Marshall Urist | EVP, Research & Investments | Sale of securities on an exchange or to another person at price $ 37.30 per share. | 22 Feb 2023 | 23,333 | 46,667 | - | 37.3 | 870,239 | Class A Ordinary Shares |
| Rory B. Riggs | Director | 17 Feb 2023 | 1,500,000 | 1,596,712 | - | 0 | Class A Ordinary Shares | ||
| Rory B. Riggs | Director | 17 Feb 2023 | 150,000 | 384,059 | - | - | LP interests in RPI US Partners 2019, LP | ||
| Marshall Urist | EVP, Research & Investments | 17 Feb 2023 | 7,000 | 128,594 | - | - | LP interests in RPI US Partners 2019, LP | ||
| Marshall Urist | EVP, Research & Investments | 17 Feb 2023 | 70,000 | 70,000 | - | 0 | Class A Ordinary Shares | ||
| Pablo Legorreta | Director, CEO, Chairman of the Board, Ten Percent Owner | Gift of securities by or to the insider at price $ 0.00 per share. | 31 Dec 2022 | 150,640 | 2,700,000 | - | - | LP interests in RPI US Partners 2019, LP | |
| Henry A. Fernandez | Director | Grant, award, or other acquisition of securities at price $ 39.76 per share. | 30 Dec 2022 | 943 | 27,987 | - | 39.8 | 37,495 | Class A Ordinary Shares |
| Bonnie L. Bassler | Director | Grant, award, or other acquisition of securities at price $ 39.76 per share. | 30 Dec 2022 | 943 | 33,781 | - | 39.8 | 37,495 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 41.98 per share. | 09 Dec 2022 | 40,010 | 96,712 | - | 42.0 | 1,679,684 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 42.07 per share. | 09 Dec 2022 | 19,990 | 136,722 | - | 42.1 | 840,939 | Class A Ordinary Shares |
| M. Germano Giuliani | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 43.15 per share. | 05 Dec 2022 | 84,302 | 7,795,072 | - | 43.1 | 3,637,463 | Class A Ordinary Shares |
| M. Germano Giuliani | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 43.98 per share. | 01 Dec 2022 | 197,766 | 7,879,374 | - | 44.0 | 8,697,412 | Class A Ordinary Shares |
| M. Germano Giuliani | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 44.10 per share. | 01 Dec 2022 | 165,000 | 22,225,000 | - | 44.1 | 7,277,325 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & CLO | Sale of securities on an exchange or to another person at price $ 43.11 per share. | 21 Nov 2022 | 20,531 | 144,469 | - | 43.1 | 885,081 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & CLO | Sale of securities on an exchange or to another person at price $ 43.14 per share. | 21 Nov 2022 | 1,900 | 350,000 | - | 43.1 | 81,969 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & CLO | Sale of securities on an exchange or to another person at price $ 43.19 per share. | 21 Nov 2022 | 14,469 | 130,000 | - | 43.2 | 624,878 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & CLO | Sale of securities on an exchange or to another person at price $ 43.11 per share. | 21 Nov 2022 | 3,100 | 351,900 | - | 43.1 | 133,638 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 42.33 per share. | 17 Nov 2022 | 120,000 | 156,712 | - | 42.3 | 5,079,924 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & CLO | Gift of securities by or to the insider at price $ 0.00 per share. | 10 Nov 2022 | 5,889 | 0 | - | - | LP interests in RPI US Partners 2019, LP | |
| George Lloyd | EVP, Investments & CLO | Sale of securities on an exchange or to another person at price $ 43.85 per share. | 10 Nov 2022 | 25,000 | 165,000 | - | 43.9 | 1,096,325 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & CLO | Sale of securities on an exchange or to another person at price $ 43.85 per share. | 10 Nov 2022 | 25,000 | 355,000 | - | 43.9 | 1,096,288 | Class A Ordinary Shares |
| Terrance Coyne | EVP & CFO | Sale of securities on an exchange or to another person at price $ 43.47 per share. | 08 Nov 2022 | 24,500 | 940,000 | - | 43.5 | 1,065,013 | Class A Ordinary Shares |
| Terrance Coyne | EVP & CFO | Sale of securities on an exchange or to another person at price $ 43.06 per share. | 02 Nov 2022 | 5,500 | 964,500 | - | 43.1 | 236,846 | Class A Ordinary Shares |
| Henry A. Fernandez | Director | Grant, award, or other acquisition of securities at price $ 41.06 per share. | 30 Sep 2022 | 913 | 27,044 | - | 41.1 | 37,490 | Class A Ordinary Shares |
| Bonnie L. Bassler | Director | Grant, award, or other acquisition of securities at price $ 41.06 per share. | 30 Sep 2022 | 913 | 32,838 | - | 41.1 | 37,490 | Class A Ordinary Shares |
| James Reddoch | EVP & Chief Scientific Officer | Gift of securities by or to the insider at price $ 0.00 per share. | 28 Sep 2022 | 2,400 | 478,870 | - | - | LP interests in RPI US Partners 2019, LP | |
| James Reddoch | EVP & Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 41.23 per share. | 28 Sep 2022 | 100,000 | 820,800 | - | 41.2 | 4,122,670 | Class A Ordinary Shares |
| M. Germano Giuliani | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 41.05 per share. | 28 Sep 2022 | 32,593 | 8,077,140 | - | 41.1 | 1,337,943 | Class A Ordinary Shares |
| M. Germano Giuliani | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 41.17 per share. | 22 Sep 2022 | 211,380 | 8,109,733 | - | 41.2 | 8,702,113 | Class A Ordinary Shares |
| M. Germano Giuliani | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 41.02 per share. | 20 Sep 2022 | 130,330 | 8,446,810 | - | 41.0 | 5,345,511 | Class A Ordinary Shares |
| M. Germano Giuliani | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 41.25 per share. | 20 Sep 2022 | 125,697 | 8,321,113 | - | 41.3 | 5,185,378 | Class A Ordinary Shares |
| M. Germano Giuliani | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 41.02 per share. | 20 Sep 2022 | 267,815 | 22,390,000 | - | 41.0 | 10,985,664 | Class A Ordinary Shares |
| M. Germano Giuliani | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 41.50 per share. | 16 Sep 2022 | 232,185 | 22,657,815 | - | 41.5 | 9,635,678 | Class A Ordinary Shares |
| M. Germano Giuliani | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 41.72 per share. | 16 Sep 2022 | 154,986 | 22,890,000 | - | 41.7 | 6,466,140 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 42.41 per share. | 14 Sep 2022 | 47,975 | 328,737 | - | 42.4 | 2,034,428 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 42.21 per share. | 14 Sep 2022 | 52,025 | 276,712 | - | 42.2 | 2,195,960 | Class A Ordinary Shares |
| M. Germano Giuliani | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 42.26 per share. | 14 Sep 2022 | 154,154 | 23,044,986 | - | 42.3 | 6,514,887 | Class A Ordinary Shares |
| M. Germano Giuliani | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 42.48 per share. | 14 Sep 2022 | 190,860 | 23,199,140 | - | 42.5 | 8,108,038 | Class A Ordinary Shares |
| M. Germano Giuliani | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 42.74 per share. | 07 Sep 2022 | 237,619 | 8,577,140 | - | 42.7 | 10,155,598 | Class A Ordinary Shares |
| M. Germano Giuliani | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 42.66 per share. | 07 Sep 2022 | 261,881 | 8,814,759 | - | 42.7 | 11,171,739 | Class A Ordinary Shares |
| M. Germano Giuliani | Director, Ten Percent Owner | Sale of securities on an exchange or to another person at price $ 44.00 per share. | 25 Aug 2022 | 500 | 9,076,640 | - | 44 | 22,000 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 43.73 per share. | 09 Aug 2022 | 45,000 | 376,712 | - | 43.7 | 1,967,823 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 43.92 per share. | 09 Aug 2022 | 11,859 | 210,109 | - | 43.9 | 520,801 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 43.93 per share. | 09 Aug 2022 | 8,995 | 201,114 | - | 43.9 | 395,108 | Class A Ordinary Shares |
| Terrance Coyne | EVP & CFO | Sale of securities on an exchange or to another person at price $ 43.19 per share. | 01 Aug 2022 | 30,000 | 970,000 | - | 43.2 | 1,295,727 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 43.97 per share. | 28 Jul 2022 | 4,046 | 221,968 | - | 44.0 | 177,893 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 42.98 per share. | 25 Jul 2022 | 11,114 | 228,886 | - | 43.0 | 477,642 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 43.90 per share. | 25 Jul 2022 | 100 | 226,014 | - | 43.9 | 4,390 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 43.76 per share. | 25 Jul 2022 | 25,000 | 380,000 | - | 43.8 | 1,094,055 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 43.12 per share. | 25 Jul 2022 | 13,886 | 226,114 | - | 43.1 | 598,824 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 43.03 per share. | 25 Jul 2022 | 5,443 | 405,000 | - | 43.0 | 234,223 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 42.90 per share. | 25 Jul 2022 | 19,557 | 410,443 | - | 42.9 | 839,066 | Class A Ordinary Shares |
| Marshall Urist | EVP, Research & Investments | Sale of securities on an exchange or to another person at price $ 43.05 per share. | 25 Jul 2022 | 3,600 | 19,734 | - | 43.1 | 154,985 | Class A Ordinary Shares |
| Marshall Urist | EVP, Research & Investments | Sale of securities on an exchange or to another person at price $ 43.20 per share. | 25 Jul 2022 | 19,734 | 0 | - | 43.2 | 852,461 | Class A Ordinary Shares |
| David C. Hodgson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 Jul 2022 | 2,346 | 8,674 | - | 0 | Class A Ordinary Shares | |
| Henry A. Fernandez | Director | Grant, award, or other acquisition of securities at price $ 41.52 per share. | 30 Jun 2022 | 903 | 26,131 | - | 41.5 | 37,493 | Class A Ordinary Shares |
| Bonnie L. Bassler | Director | Grant, award, or other acquisition of securities at price $ 41.52 per share. | 30 Jun 2022 | 903 | 31,925 | - | 41.5 | 37,493 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 42.17 per share. | 29 Jun 2022 | 30,000 | 421,712 | - | 42.2 | 1,265,238 | Class A Ordinary Shares |
| David C. Hodgson | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jun 2022 | 6,328 | 6,328 | - | 0 | Class A Ordinary Shares | |
| Henry A. Fernandez | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jun 2022 | 6,328 | 25,228 | - | 0 | Class A Ordinary Shares | |
| Gregory Norden | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jun 2022 | 6,328 | 56,698 | - | 0 | Class A Ordinary Shares | |
| Ted W. Love | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jun 2022 | 6,328 | 29,194 | - | 0 | Class A Ordinary Shares | |
| Bonnie L. Bassler | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jun 2022 | 6,328 | 31,022 | - | 0 | Class A Ordinary Shares | |
| Catherine M. Engelbert | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 24 Jun 2022 | 6,328 | 25,464 | - | 0 | Class A Ordinary Shares | |
| Marshall Urist | EVP, Research & Investments | Sale of securities on an exchange or to another person at price $ 43.19 per share. | 24 Jun 2022 | 23,333 | 23,334 | - | 43.2 | 1,007,694 | Class A Ordinary Shares |
| James Reddoch | EVP & Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 41.56 per share. | 08 Jun 2022 | 100,000 | 920,800 | - | 41.6 | 4,155,900 | Class A Ordinary Shares |
| James Reddoch | EVP & Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 41.08 per share. | 27 May 2022 | 75,000 | 1,020,800 | - | 41.1 | 3,081,008 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 40.77 per share. | 26 May 2022 | 13,974 | 430,000 | - | 40.8 | 569,754 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 40.21 per share. | 26 May 2022 | 86,026 | 443,974 | - | 40.2 | 3,459,338 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 40.27 per share. | 23 May 2022 | 100,000 | 530,000 | - | 40.3 | 4,026,770 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 39.28 per share. | 19 May 2022 | 123,696 | 451,712 | - | 39.3 | 4,858,655 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 40.09 per share. | 19 May 2022 | 26,304 | 575,408 | - | 40.1 | 1,054,651 | Class A Ordinary Shares |
| James Reddoch | EVP & Chief Scientific Officer | Sale of securities on an exchange or to another person at price $ 40.44 per share. | 19 May 2022 | 75,000 | 1,095,800 | - | 40.4 | 3,033,128 | Class A Ordinary Shares |
| Marshall Urist | EVP, Research & Investments | Sale of securities on an exchange or to another person at price $ 39.85 per share. | 16 May 2022 | 23,333 | 46,667 | - | 39.9 | 929,836 | Class A Ordinary Shares |
| Marshall Urist | EVP, Research & Investments | 11 May 2022 | 70,000 | 70,000 | - | 0 | Class A Ordinary Shares | ||
| Marshall Urist | EVP, Research & Investments | 11 May 2022 | 7,000 | 205,594 | - | - | LP interests in RPI US Partners 2019, LP | ||
| Henry A. Fernandez | Director | Grant, award, or other acquisition of securities at price $ 38.87 per share. | 31 Mar 2022 | 964 | 18,900 | - | 38.9 | 37,471 | Class A Ordinary Shares |
| Bonnie L. Bassler | Director | Grant, award, or other acquisition of securities at price $ 38.87 per share. | 31 Mar 2022 | 964 | 24,694 | - | 38.9 | 37,471 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 38.59 per share. | 29 Mar 2022 | 60,000 | 601,712 | - | 38.6 | 2,315,322 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Other type of transaction at price $ 0.00 per share. | 17 Mar 2022 | 229,626 | 72,348 | - | - | Class A Ordinary Shares | |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 39.05 per share. | 17 Mar 2022 | 14,322 | 0 | - | 39.1 | 559,288 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 39.05 per share. | 17 Mar 2022 | 25,545 | 0 | - | 39.1 | 997,558 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 39.77 per share. | 17 Mar 2022 | 56,181 | 85,187 | - | 39.8 | 2,234,094 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 39.38 per share. | 17 Mar 2022 | 26,238 | 14,322 | - | 39.4 | 1,033,334 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 39.38 per share. | 17 Mar 2022 | 46,803 | 25,545 | - | 39.4 | 1,843,247 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Other type of transaction at price $ 0.00 per share. | 17 Mar 2022 | 531,684 | 141,368 | - | - | Class A Ordinary Shares | |
| Rory B. Riggs | Director | Other type of transaction at price $ 0.00 per share. | 17 Mar 2022 | 1,075,178 | 40,560 | - | - | Class A Ordinary Shares | |
| Rory B. Riggs | Director | Other type of transaction at price $ 0.00 per share. | 17 Mar 2022 | 64,067 | 661,712 | - | - | Class A Ordinary Shares | |
| Rory B. Riggs | Director | Other type of transaction at price $ 0.00 per share. | 17 Mar 2022 | 4,897 | 597,645 | - | - | Class A Ordinary Shares | |
| Rory B. Riggs | Director | Other type of transaction at price $ 0.00 per share. | 28 Dec 2021 | 42,138 | 667,748 | - | - | Class A Ordinary Shares | |
| Rory B. Riggs | Director | Other type of transaction at price $ 0.00 per share. | 28 Dec 2021 | 3,212 | 625,610 | - | - | Class A Ordinary Shares | |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 40.00 per share. | 28 Dec 2021 | 75,000 | 592,748 | - | 40.0 | 3,000,353 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 40.21 per share. | 28 Dec 2021 | 35,193 | 673,052 | - | 40.2 | 1,414,963 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 40.21 per share. | 28 Dec 2021 | 26,677 | 1,115,738 | - | 40.2 | 1,072,559 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 40.21 per share. | 28 Dec 2021 | 47,578 | 301,974 | - | 40.2 | 1,912,893 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Other type of transaction at price $ 0.00 per share. | 28 Dec 2021 | 407,400 | 708,245 | - | - | Class A Ordinary Shares | |
| Rory B. Riggs | Director | Other type of transaction at price $ 0.00 per share. | 28 Dec 2021 | 707,155 | 1,142,415 | - | - | Class A Ordinary Shares | |
| Rory B. Riggs | Director | Other type of transaction at price $ 0.00 per share. | 28 Dec 2021 | 150,997 | 349,552 | - | - | Class A Ordinary Shares | |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 42.01 per share. | 16 Nov 2021 | 12,565 | 684,833 | - | 42.0 | 527,805 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Other type of transaction at price $ 0.00 per share. | 16 Nov 2021 | 4,674 | 636,060 | - | - | Class A Ordinary Shares | |
| Rory B. Riggs | Director | Other type of transaction at price $ 0.00 per share. | 16 Nov 2021 | 61,338 | 697,398 | - | - | Class A Ordinary Shares | |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 42.33 per share. | 16 Nov 2021 | 31,341 | 1,115,645 | - | 42.3 | 1,326,636 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 42.35 per share. | 16 Nov 2021 | 38,815 | 1,849,570 | - | 42.3 | 1,643,749 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 42.35 per share. | 16 Nov 2021 | 69,233 | 500,549 | - | 42.3 | 2,931,900 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 42.39 per share. | 16 Nov 2021 | 62,435 | 622,398 | - | 42.4 | 2,646,401 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Other type of transaction at price $ 0.00 per share. | 16 Nov 2021 | 612,668 | 1,146,986 | - | - | Class A Ordinary Shares | |
| Rory B. Riggs | Director | Other type of transaction at price $ 0.00 per share. | 16 Nov 2021 | 1,028,973 | 1,888,385 | - | - | Class A Ordinary Shares | |
| Rory B. Riggs | Director | Other type of transaction at price $ 0.00 per share. | 16 Nov 2021 | 219,710 | 569,782 | - | - | Class A Ordinary Shares | |
| George Lloyd | EVP, Investments & GC | Gift of securities by or to the insider at price $ 0.00 per share. | 16 Nov 2021 | 1,282 | 5,889 | - | - | LP interests in RPI US Partners 2019, LP | |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 42.39 per share. | 16 Nov 2021 | 84,148 | 630,000 | - | 42.4 | 3,566,832 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 42.12 per share. | 16 Nov 2021 | 65,852 | 714,148 | - | 42.1 | 2,773,660 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 43.19 per share. | 16 Nov 2021 | 27,341 | 495,860 | - | 43.2 | 1,180,822 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 42.33 per share. | 16 Nov 2021 | 72,659 | 523,201 | - | 42.3 | 3,075,379 | Class A Ordinary Shares |
| Henry A. Fernandez | Director | Grant, award, or other acquisition of securities at price $ 37.80 per share. | 30 Sep 2021 | 992 | 16,978 | - | 37.8 | 37,499 | Class A Ordinary Shares |
| Bonnie L. Bassler | Director | Grant, award, or other acquisition of securities at price $ 37.80 per share. | 30 Sep 2021 | 992 | 22,772 | - | 37.8 | 37,499 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Other type of transaction at price $ 0.00 per share. | 28 Sep 2021 | 314,886 | 1,759,654 | - | - | Class A Ordinary Shares | |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 36.67 per share. | 28 Sep 2021 | 7,000 | 2,074,540 | - | 36.7 | 256,671 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Other type of transaction at price $ 0.00 per share. | 28 Sep 2021 | 511,727 | 2,917,358 | - | - | Class A Ordinary Shares | |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 36.31 per share. | 28 Sep 2021 | 22,173 | 3,429,085 | - | 36.3 | 805,199 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Other type of transaction at price $ 0.00 per share. | 28 Sep 2021 | 109,814 | 789,492 | - | - | Class A Ordinary Shares | |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 36.31 per share. | 28 Sep 2021 | 34,604 | 899,306 | - | 36.3 | 1,256,623 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Other type of transaction at price $ 0.00 per share. | 28 Sep 2021 | 8,641 | 631,386 | - | - | Class A Ordinary Shares | |
| Rory B. Riggs | Director | Other type of transaction at price $ 0.00 per share. | 28 Sep 2021 | 5,299 | 622,745 | - | - | Class A Ordinary Shares | |
| Rory B. Riggs | Director | Other type of transaction at price $ 0.00 per share. | 28 Sep 2021 | 2,334 | 617,446 | - | - | Class A Ordinary Shares | |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 36.50 per share. | 28 Sep 2021 | 24,648 | 615,112 | - | 36.5 | 899,706 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 36.75 per share. | 28 Sep 2021 | 40,000 | 639,760 | - | 36.8 | 1,470,088 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Gift of securities by or to the insider at price $ 0.00 per share. | 28 Sep 2021 | 7,692 | 534,059 | - | - | LP interests in RPI US Partners 2019, LP | |
| James Reddoch | EVP, Research & Investments | Gift of securities by or to the insider at price $ 0.00 per share. | 10 Sep 2021 | 5,128 | 481,270 | - | - | LP interests in RPI US Partners 2019, LP | |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 39.76 per share. | 26 Jul 2021 | 8,449 | 780,000 | - | 39.8 | 335,942 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 39.81 per share. | 26 Jul 2021 | 4,913 | 595,860 | - | 39.8 | 195,591 | Class A Ordinary Shares |
| James Reddoch | EVP, Research & Investments | Sale of securities on an exchange or to another person at price $ 39.78 per share. | 26 Jul 2021 | 8,949 | 1,170,800 | - | 39.8 | 355,977 | Class A Ordinary Shares |
| James Reddoch | EVP, Research & Investments | Sale of securities on an exchange or to another person at price $ 39.78 per share. | 26 Jul 2021 | 8,949 | 1,170,800 | - | 39.8 | 355,977 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 42.01 per share. | 12 Jul 2021 | 5,068 | 600,773 | - | 42.0 | 212,890 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 42.01 per share. | 12 Jul 2021 | 17,981 | 788,449 | - | 42.0 | 755,362 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 42.04 per share. | 12 Jul 2021 | 100 | 806,430 | - | 42.0 | 4,204 | Class A Ordinary Shares |
| James Reddoch | EVP, Research & Investments | Sale of securities on an exchange or to another person at price $ 42.00 per share. | 12 Jul 2021 | 2 | 1,179,749 | - | 42 | 84 | Class A Ordinary Shares |
| James Reddoch | EVP, Research & Investments | Sale of securities on an exchange or to another person at price $ 42.01 per share. | 12 Jul 2021 | 17,832 | 1,179,751 | - | 42.0 | 749,081 | Class A Ordinary Shares |
| James Reddoch | EVP, Research & Investments | Sale of securities on an exchange or to another person at price $ 42.04 per share. | 12 Jul 2021 | 100 | 1,197,583 | - | 42.0 | 4,204 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 42.41 per share. | 06 Jul 2021 | 30,303 | 849,697 | - | 42.4 | 1,285,026 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 42.05 per share. | 06 Jul 2021 | 8,392 | 605,841 | - | 42.1 | 352,888 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 42.01 per share. | 06 Jul 2021 | 2,500 | 847,197 | - | 42.0 | 105,022 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 42.02 per share. | 06 Jul 2021 | 400 | 614,233 | - | 42.0 | 16,806 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 42.42 per share. | 06 Jul 2021 | 6,227 | 614,633 | - | 42.4 | 264,119 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 42.05 per share. | 06 Jul 2021 | 40,667 | 806,530 | - | 42.0 | 1,709,901 | Class A Ordinary Shares |
| James Reddoch | EVP, Research & Investments | Sale of securities on an exchange or to another person at price $ 42.05 per share. | 06 Jul 2021 | 40,655 | 1,197,683 | - | 42.0 | 1,709,380 | Class A Ordinary Shares |
| James Reddoch | EVP, Research & Investments | Sale of securities on an exchange or to another person at price $ 42.01 per share. | 06 Jul 2021 | 2,192 | 1,238,338 | - | 42.0 | 92,087 | Class A Ordinary Shares |
| James Reddoch | EVP, Research & Investments | Sale of securities on an exchange or to another person at price $ 42.40 per share. | 06 Jul 2021 | 30,270 | 1,240,530 | - | 42.4 | 1,283,560 | Class A Ordinary Shares |
| Henry A. Fernandez | Director | Grant, award, or other acquisition of securities at price $ 43.04 per share. | 30 Jun 2021 | 871 | 15,986 | - | 43.0 | 37,489 | Class A Ordinary Shares |
| William E. Ford | Director | Grant, award, or other acquisition of securities at price $ 43.04 per share. | 30 Jun 2021 | 871 | 6,597 | - | 43.0 | 37,489 | Class A Ordinary Shares |
| Bonnie L. Bassler | Director | Grant, award, or other acquisition of securities at price $ 43.04 per share. | 30 Jun 2021 | 871 | 21,780 | - | 43.0 | 37,489 | Class A Ordinary Shares |
| Henry A. Fernandez | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2021 | 5,726 | 15,115 | - | 0 | Class A Ordinary Shares | |
| Gregory Norden | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2021 | 5,726 | 50,370 | - | 0 | Class A Ordinary Shares | |
| Ted W. Love | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2021 | 5,726 | 22,866 | - | 0 | Class A Ordinary Shares | |
| William E. Ford | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2021 | 5,726 | 5,726 | - | 0 | Class A Ordinary Shares | |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 42.01 per share. | 25 Jun 2021 | 1,200 | 3,931,058 | - | 42.0 | 50,409 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 41.26 per share. | 25 Jun 2021 | 479,800 | 3,451,258 | - | 41.3 | 19,794,437 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 42.11 per share. | 25 Jun 2021 | 167,448 | 3,932,258 | - | 42.1 | 7,051,269 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 42.69 per share. | 25 Jun 2021 | 487,364 | 4,099,706 | - | 42.7 | 20,807,519 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 42.81 per share. | 25 Jun 2021 | 179,100 | 933,910 | - | 42.8 | 7,666,501 | Class A Ordinary Shares |
| Bonnie L. Bassler | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2021 | 5,726 | 20,909 | - | 0 | Class A Ordinary Shares | |
| Catherine M. Engelbert | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Jun 2021 | 5,726 | 19,136 | - | 0 | Class A Ordinary Shares | |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 46.45 per share. | 10 Jun 2021 | 10,000 | 240,000 | - | 46.4 | 464,491 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 46.46 per share. | 10 Jun 2021 | 20,000 | 620,860 | - | 46.5 | 929,106 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 46.52 per share. | 10 Jun 2021 | 40,000 | 880,000 | - | 46.5 | 1,860,772 | Class A Ordinary Shares |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 45.26 per share. | 07 Jun 2021 | 273,650 | 2,081,540 | - | 45.3 | 12,385,399 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 45.97 per share. | 04 Jun 2021 | 19,100 | 674,260 | - | 46.0 | 878,077 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 46.47 per share. | 04 Jun 2021 | 10,000 | 250,000 | - | 46.5 | 464,747 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 46.48 per share. | 04 Jun 2021 | 40,000 | 920,000 | - | 46.5 | 1,859,344 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 46.48 per share. | 04 Jun 2021 | 20,000 | 640,860 | - | 46.5 | 929,540 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 44.69 per share. | 04 Jun 2021 | 20,000 | 693,360 | - | 44.7 | 893,706 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 44.85 per share. | 04 Jun 2021 | 20,000 | 1,030,000 | - | 44.9 | 897,028 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 44.81 per share. | 04 Jun 2021 | 20,000 | 280,000 | - | 44.8 | 896,204 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 46.54 per share. | 04 Jun 2021 | 4,853 | 260,000 | - | 46.5 | 225,859 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 45.89 per share. | 04 Jun 2021 | 15,147 | 264,853 | - | 45.9 | 695,109 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 46.74 per share. | 04 Jun 2021 | 36,619 | 960,000 | - | 46.7 | 1,711,697 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 46.10 per share. | 04 Jun 2021 | 33,381 | 996,619 | - | 46.1 | 1,538,767 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 46.77 per share. | 04 Jun 2021 | 13,400 | 660,860 | - | 46.8 | 626,719 | Class A Ordinary Shares |
| James Reddoch | EVP, Research & Investments | Sale of securities on an exchange or to another person at price $ 46.57 per share. | 04 Jun 2021 | 47,790 | 1,323,010 | - | 46.6 | 2,225,523 | Class A Ordinary Shares |
| James Reddoch | EVP, Research & Investments | Sale of securities on an exchange or to another person at price $ 46.43 per share. | 04 Jun 2021 | 50,000 | 1,270,800 | - | 46.4 | 2,321,540 | Class A Ordinary Shares |
| James Reddoch | EVP, Research & Investments | Sale of securities on an exchange or to another person at price $ 47.01 per share. | 04 Jun 2021 | 2,210 | 1,320,800 | - | 47.0 | 103,896 | Class A Ordinary Shares |
| James Reddoch | EVP, Research & Investments | Sale of securities on an exchange or to another person at price $ 44.60 per share. | 04 Jun 2021 | 100,000 | 1,370,800 | - | 44.6 | 4,459,730 | Class A Ordinary Shares |
| Marshall Urist | EVP & Co-Head of R&I | Sale of securities on an exchange or to another person at price $ 47.02 per share. | 04 Jun 2021 | 16,568 | 0 | - | 47.0 | 779,059 | Class A Ordinary Shares |
| Marshall Urist | EVP & Co-Head of R&I | Sale of securities on an exchange or to another person at price $ 45.13 per share. | 04 Jun 2021 | 16,566 | 16,568 | - | 45.1 | 747,662 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 42.13 per share. | 02 Jun 2021 | 50,000 | 1,050,000 | - | 42.1 | 2,106,385 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 42.09 per share. | 02 Jun 2021 | 12,500 | 713,360 | - | 42.1 | 526,128 | Class A Ordinary Shares |
| James Reddoch | EVP, Research & Investments | Sale of securities on an exchange or to another person at price $ 42.13 per share. | 02 Jun 2021 | 50,000 | 1,470,800 | - | 42.1 | 2,106,560 | Class A Ordinary Shares |
| Marshall Urist | EVP & Co-Head Research & Inv. | Sale of securities on an exchange or to another person at price $ 41.52 per share. | 02 Jun 2021 | 14,566 | 33,134 | - | 41.5 | 604,850 | Class A Ordinary Shares |
| Marshall Urist | EVP & Co-Head Research & Inv. | Sale of securities on an exchange or to another person at price $ 41.00 per share. | 20 May 2021 | 100 | 47,700 | - | 41 | 4,100 | Class A Ordinary Shares |
| Marshall Urist | EVP & Co-Head Research & Inv. | Sale of securities on an exchange or to another person at price $ 41.08 per share. | 20 May 2021 | 1,900 | 47,800 | - | 41.1 | 78,059 | Class A Ordinary Shares |
| Rory B. Riggs | Director | 07 May 2021 | 679,760 | 679,760 | - | 0 | Class A Ordinary Shares | ||
| Rory B. Riggs | Director | 07 May 2021 | 2,355,190 | 2,355,190 | - | 0 | Class A Ordinary Shares | ||
| Rory B. Riggs | Director | 07 May 2021 | 235,519 | 0 | - | - | LP interests in RPI US Partners 2019, LP | ||
| Rory B. Riggs | Director | 07 May 2021 | 67,976 | 541,751 | - | - | LP interests in RPI US Partners 2019, LP | ||
| Pablo Legorreta | Director, CEO, Chairman of the Board | 07 May 2021 | 1,040,410 | 1,040,410 | - | 0 | Class A Ordinary Shares | ||
| Pablo Legorreta | Director, CEO, Chairman of the Board | 07 May 2021 | 128,459 | 0 | - | - | LP interests in RPI US Partners 2019, LP | ||
| Pablo Legorreta | Director, CEO, Chairman of the Board | 07 May 2021 | 104,041 | 0 | - | - | LP interests in RPI US Partners 2019, LP | ||
| Pablo Legorreta | Director, CEO, Chairman of the Board | 07 May 2021 | 1,284,590 | 1,284,590 | - | 0 | Class A Ordinary Shares | ||
| Terrance Coyne | EVP & CFO | 07 May 2021 | 100,000 | 22,945 | - | - | LP interests in RPI US Partners 2019, LP | ||
| Terrance Coyne | EVP & CFO | 07 May 2021 | 1,000,000 | 1,000,000 | - | 0 | Class A Ordinary Shares | ||
| George Lloyd | EVP, Investments & GC | 07 May 2021 | 90,000 | 172,680 | - | - | LP interests in RPI US Partners 2019, LP | ||
| George Lloyd | EVP, Investments & GC | 07 May 2021 | 67,586 | 0 | - | - | LP interests in RPI US Partners 2019, LP | ||
| George Lloyd | EVP, Investments & GC | 07 May 2021 | 300,000 | 300,000 | - | 0 | Class A Ordinary Shares | ||
| George Lloyd | EVP, Investments & GC | 07 May 2021 | 900,000 | 1,100,000 | - | 0 | Class A Ordinary Shares | ||
| George Lloyd | EVP, Investments & GC | 07 May 2021 | 675,860 | 725,860 | - | 0 | Class A Ordinary Shares | ||
| George Lloyd | EVP, Investments & GC | 07 May 2021 | 30,000 | 264,027 | - | - | LP interests in RPI US Partners 2019, LP | ||
| James Reddoch | EVP, Research & Investments | 07 May 2021 | 132,080 | 486,398 | - | - | LP interests in RPI US Partners 2019, LP | ||
| James Reddoch | EVP, Research & Investments | 07 May 2021 | 1,320,800 | 1,520,800 | - | 0 | Class A Ordinary Shares | ||
| Marshall Urist | EVP & Co-Head Research & Inv. | 07 May 2021 | 49,700 | 49,700 | - | 0 | Class A Ordinary Shares | ||
| Marshall Urist | EVP & Co-Head Research & Inv. | 07 May 2021 | 4,970 | 142,594 | - | - | LP interests in RPI US Partners 2019, LP | ||
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 42.12 per share. | 14 Apr 2021 | 13,924 | 50,000 | - | 42.1 | 586,434 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 42.14 per share. | 14 Apr 2021 | 55,898 | 200,000 | - | 42.1 | 2,355,486 | Class A Ordinary Shares |
| James Reddoch | EVP, Research & Investments | Sale of securities on an exchange or to another person at price $ 42.10 per share. | 14 Apr 2021 | 55,714 | 200,000 | - | 42.1 | 2,345,593 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 42.32 per share. | 12 Apr 2021 | 360 | 255,898 | - | 42.3 | 15,235 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 42.31 per share. | 12 Apr 2021 | 89 | 63,924 | - | 42.3 | 3,766 | Class A Ordinary Shares |
| James Reddoch | EVP, Research & Investments | Sale of securities on an exchange or to another person at price $ 42.32 per share. | 12 Apr 2021 | 359 | 255,714 | - | 42.3 | 15,193 | Class A Ordinary Shares |
| Henry A. Fernandez | Director | Grant, award, or other acquisition of securities at price $ 45.90 per share. | 31 Mar 2021 | 816 | 9,529 | - | 45.9 | 37,458 | Class A Ordinary Shares |
| Bonnie L. Bassler | Director | Grant, award, or other acquisition of securities at price $ 45.90 per share. | 31 Mar 2021 | 816 | 15,183 | - | 45.9 | 37,458 | Class A Ordinary Shares |
| Christopher Hite | EVP & Vice Chairman | Sale of securities on an exchange or to another person at price $ 0.00 per share. | 23 Mar 2021 | 31,959 | 30,541 | - | - | LP interests in RPI US Partners 2019, LP | |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 46.32 per share. | 22 Mar 2021 | 43,642 | 256,358 | - | 46.3 | 2,021,436 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 47.04 per share. | 22 Mar 2021 | 100 | 256,258 | - | 47.0 | 4,704 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 46.34 per share. | 22 Mar 2021 | 10,987 | 64,013 | - | 46.3 | 509,086 | Class A Ordinary Shares |
| James Reddoch | EVP, Research & Investments | Sale of securities on an exchange or to another person at price $ 46.32 per share. | 22 Mar 2021 | 43,927 | 256,073 | - | 46.3 | 2,034,519 | Class A Ordinary Shares |
| Terrance Coyne | EVP & CFO | Sale of securities on an exchange or to another person at price $ 46.83 per share. | 03 Mar 2021 | 1,456 | 200,000 | - | 46.8 | 68,184 | Class A Ordinary Shares |
| Terrance Coyne | EVP & CFO | Sale of securities on an exchange or to another person at price $ 45.86 per share. | 03 Mar 2021 | 11,001 | 201,456 | - | 45.9 | 504,459 | Class A Ordinary Shares |
| Terrance Coyne | EVP & CFO | Sale of securities on an exchange or to another person at price $ 43.71 per share. | 03 Mar 2021 | 29,820 | 270,180 | - | 43.7 | 1,303,343 | Class A Ordinary Shares |
| Terrance Coyne | EVP & CFO | Sale of securities on an exchange or to another person at price $ 45.09 per share. | 03 Mar 2021 | 57,723 | 212,457 | - | 45.1 | 2,602,465 | Class A Ordinary Shares |
| Terrance Coyne | EVP & CFO | Sale of securities on an exchange or to another person at price $ 46.89 per share. | 02 Mar 2021 | 94,978 | 305,022 | - | 46.9 | 4,453,661 | Class A Ordinary Shares |
| Terrance Coyne | EVP & CFO | Sale of securities on an exchange or to another person at price $ 47.88 per share. | 02 Mar 2021 | 5,022 | 300,000 | - | 47.9 | 240,429 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 46.89 per share. | 02 Mar 2021 | 22,375 | 77,625 | - | 46.9 | 1,049,258 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 47.85 per share. | 02 Mar 2021 | 3,510 | 300,000 | - | 47.8 | 167,948 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 46.89 per share. | 02 Mar 2021 | 96,490 | 303,510 | - | 46.9 | 4,524,368 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Sale of securities on an exchange or to another person at price $ 47.84 per share. | 02 Mar 2021 | 2,625 | 75,000 | - | 47.8 | 125,575 | Class A Ordinary Shares |
| James Reddoch | EVP, Research & Investments | Sale of securities on an exchange or to another person at price $ 47.84 per share. | 02 Mar 2021 | 3,510 | 300,000 | - | 47.8 | 167,925 | Class A Ordinary Shares |
| James Reddoch | EVP, Research & Investments | Sale of securities on an exchange or to another person at price $ 46.89 per share. | 02 Mar 2021 | 96,490 | 303,510 | - | 46.9 | 4,524,233 | Class A Ordinary Shares |
| Henry A. Fernandez | Director | Purchase of securities on an exchange or from another person at price $ 46.83 per share. | 25 Feb 2021 | 25,700 | 25,700 | - | 46.8 | 1,203,480 | Class A Ordinary Shares |
| Henry A. Fernandez | Director | Grant, award, or other acquisition of securities at price $ 45.69 per share. | 31 Dec 2020 | 820 | 8,713 | - | 45.7 | 37,464 | Class A Ordinary Shares |
| Bonnie L. Bassler | Director | Grant, award, or other acquisition of securities at price $ 45.69 per share. | 31 Dec 2020 | 820 | 14,367 | - | 45.7 | 37,464 | Class A Ordinary Shares |
| Terrance Coyne | EVP & CFO | 31 Dec 2020 | 300,230 | 400,000 | - | 0 | Class A Ordinary Shares | ||
| Terrance Coyne | EVP & CFO | 31 Dec 2020 | 9,977 | 778 | - | - | LP interests in RPI US Partners 2019, LP | ||
| Terrance Coyne | EVP & CFO | 31 Dec 2020 | 30,023 | 376,468 | - | - | LP interests in RPI US Partners 2019, LP | ||
| Terrance Coyne | EVP & CFO | 31 Dec 2020 | 99,770 | 99,770 | - | 0 | Class A Ordinary Shares | ||
| George Lloyd | EVP, Investments & GC | 31 Dec 2020 | 400,000 | 400,000 | - | 0 | Class A Ordinary Shares | ||
| George Lloyd | EVP, Investments & GC | 31 Dec 2020 | 40,000 | 556,707 | - | - | LP interests in RPI US Partners 2019, LP | ||
| George Lloyd | EVP, Investments & GC | 31 Dec 2020 | 10,000 | 73,638 | - | - | LP interests in RPI US Partners 2019, LP | ||
| George Lloyd | EVP, Investments & GC | 31 Dec 2020 | 100,000 | 100,000 | - | 0 | Class A Ordinary Shares | ||
| James Reddoch | EVP, Research & Investments | 31 Dec 2020 | 270,100 | 270,100 | - | 0 | Class A Ordinary Shares | ||
| James Reddoch | EVP, Research & Investments | 31 Dec 2020 | 12,990 | 618,478 | - | - | LP interests in RPI US Partners 2019, LP | ||
| James Reddoch | EVP, Research & Investments | 31 Dec 2020 | 27,010 | 2,107 | - | - | LP interests in RPI US Partners 2019, LP | ||
| James Reddoch | EVP, Research & Investments | 31 Dec 2020 | 129,900 | 400,000 | - | 0 | Class A Ordinary Shares | ||
| William E. Ford | Director | 20 Oct 2020 | 581,870 | 581,870 | - | 0 | Class A Ordinary Shares | ||
| William E. Ford | Director | 20 Oct 2020 | 58,187 | 0 | - | - | LP interests in RPI US Partners 2019, LP | ||
| William E. Ford | Director | Other type of transaction at price $ 0.00 per share. | 20 Oct 2020 | 42,101 | 539,769 | - | 0 | Class A Ordinary Shares | |
| Rory B. Riggs | Director | Sale of securities on an exchange or to another person at price $ 42.00 per share. | 20 Oct 2020 | 463,200 | 0 | - | 42 | 19,454,400 | Class A Ordinary Shares |
| Henry A. Fernandez | Director | Grant, award, or other acquisition of securities at price $ 41.17 per share. | 30 Sep 2020 | 613 | 7,893 | - | 41.2 | 25,240 | Class A Ordinary Shares |
| Bonnie L. Bassler | Director | Grant, award, or other acquisition of securities at price $ 41.17 per share. | 30 Sep 2020 | 910 | 13,547 | - | 41.2 | 37,468 | Class A Ordinary Shares |
| Catherine M. Engelbert | Director | Grant, award, or other acquisition of securities at price $ 41.17 per share. | 30 Sep 2020 | 910 | 13,410 | - | 41.2 | 37,468 | Class A Ordinary Shares |
| Henry A. Fernandez | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Aug 2020 | 7,280 | 7,280 | - | 0 | Class A Ordinary Shares | |
| Ted W. Love | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Aug 2020 | 7,280 | 17,280 | - | 0 | Class A Ordinary Shares | |
| Rory B. Riggs | Director | 18 Jun 2020 | 111,301 | 0 | - | - | LP interests in RPI International Holdings 2019, LP | ||
| Rory B. Riggs | Director | 18 Jun 2020 | 458,707 | 0 | - | - | LP interests in RPI International Holdings 2019, LP | ||
| Rory B. Riggs | Director | 18 Jun 2020 | 1,113,010 | 1,113,010 | - | 0 | Class A Ordinary Shares | ||
| Rory B. Riggs | Director | 18 Jun 2020 | 4,587,070 | 4,587,070 | - | 0 | Class A Ordinary Shares | ||
| Bonnie L. Bassler | Director | Grant, award, or other acquisition of securities at price $ 48.00 per share. | 18 Jun 2020 | 137 | 12,637 | - | 48 | 6,576 | Class A Ordinary Shares |
| Bonnie L. Bassler | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jun 2020 | 12,500 | 12,500 | - | 0 | Class A Ordinary Shares | |
| Catherine M. Engelbert | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jun 2020 | 12,500 | 12,500 | - | 0 | Class A Ordinary Shares | |
| Terrance Coyne | EVP & CFO | 18 Jun 2020 | 24,170 | 24,170 | - | 0 | Class A Ordinary Shares | ||
| Terrance Coyne | EVP & CFO | 18 Jun 2020 | 2,417 | 188 | - | - | LP interests in RPI International Holdings 2019, LP | ||
| Terrance Coyne | EVP & CFO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 18 Jun 2020 | 2,605 | 2,605 | - | - | LP interests in RPI International Holdings 2019, LP | |
| Pablo Legorreta | Director, CEO, Chairman of the Board, Ten Percent Owner | 16 Jun 2020 | 493,750 | 493,750 | - | 0 | Class A Ordinary Shares | ||
| Pablo Legorreta | Director, CEO, Chairman of the Board, Ten Percent Owner | 16 Jun 2020 | 428,420 | 922,170 | - | 0 | Class A Ordinary Shares | ||
| Pablo Legorreta | Director, CEO, Chairman of the Board, Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 16 Jun 2020 | 462,031 | 0 | - | 0 | Class A Ordinary Shares | |
| Pablo Legorreta | Director, CEO, Chairman of the Board, Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 16 Jun 2020 | 350,000 | 63,795 | - | 0 | Class A Ordinary Shares | |
| Pablo Legorreta | Director, CEO, Chairman of the Board, Ten Percent Owner | 16 Jun 2020 | 49,375 | 1,669,699 | - | - | ICAI Interests | ||
| Pablo Legorreta | Director, CEO, Chairman of the Board, Ten Percent Owner | 16 Jun 2020 | 49,375 | 5,797,646 | - | - | LP interests in RPI US Partners 2019, LP | ||
| Pablo Legorreta | Director, CEO, Chairman of the Board, Ten Percent Owner | 16 Jun 2020 | 49,375 | 5,748,271 | - | - | LP interests in RPI US Partners 2019, LP | ||
| Pablo Legorreta | Director, CEO, Chairman of the Board, Ten Percent Owner | 16 Jun 2020 | 42,842 | 1,626,857 | - | - | ICAI Interests | ||
| Pablo Legorreta | Director, CEO, Chairman of the Board, Ten Percent Owner | 16 Jun 2020 | 42,842 | 5,791,113 | - | - | LP interests in RPI US Partners 2019, LP | ||
| Pablo Legorreta | Director, CEO, Chairman of the Board, Ten Percent Owner | 16 Jun 2020 | 42,842 | 5,748,271 | - | - | LP interests in RPI US Partners 2019, LP | ||
| Pablo Legorreta | Director, CEO, Chairman of the Board, Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 16 Jun 2020 | 15,947 | 2,850,640 | - | - | LP interests in RPI US Partners 2019, LP | |
| Pablo Legorreta | Director, CEO, Chairman of the Board, Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 16 Jun 2020 | 16,012 | 2,862,363 | - | - | LP interests in RPI US Partners 2019, LP | |
| Pablo Legorreta | Director, CEO, Chairman of the Board, Ten Percent Owner | Other type of transaction at price $ 0.00 per share. | 16 Jun 2020 | 73,332 | 73,332 | - | - | ICAI Interests | |
| Gregory Norden | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2020 | 8,929 | 44,644 | - | 0 | Class A Ordinary Shares | |
| Gregory Norden | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2020 | 15,594 | 15,594 | - | - | LP interests in RPI US Partners 2019, LP | |
| Gregory Norden | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2020 | 35,715 | 35,715 | - | 0 | Class A Ordinary Shares | |
| William E. Ford | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2020 | 2,667,385 | 2,667,385 | - | - | LP interests in RPI US Partners 2019, LP | |
| William E. Ford | Director | Purchase of securities on an exchange or from another person at price $ 28.00 per share. | 15 Jun 2020 | 1,500,000 | 1,500,000 | - | 28 | 42,000,000 | Class A Ordinary Shares |
| William E. Ford | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2020 | 171,350 | 171,350 | - | - | LP interests in RPI US Partners 2019, LP | |
| William E. Ford | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2020 | 76,127 | 76,127 | - | - | LP interests in RPI US Partners 2019, LP | |
| Pablo Legorreta | Director, CEO, Chairman of the Board, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2020 | 1,719,074 | 1,719,074 | - | - | ICAI Interests | |
| Christopher Hite | EVP & Vice Chairman | Purchase of securities on an exchange or from another person at price $ 28.00 per share. | 15 Jun 2020 | 70,000 | 70,000 | - | 28 | 1,960,000 | Class A Ordinary Shares |
| Christopher Hite | EVP & Vice Chairman | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2020 | 62,500 | 62,500 | - | - | LP interests in RPI US Partners 2019, LP | |
| Christopher Hite | EVP & Vice Chairman | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2020 | 116,100 | 116,100 | - | - | ICAI Interests | |
| George Lloyd | EVP, Investments & GC | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2020 | 353,000 | 353,000 | - | - | ICAI Interests | |
| George Lloyd | EVP, Investments & GC | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2020 | 28,326 | 28,326 | - | - | LP interests in RPI International Holdings 2019, LP | |
| George Lloyd | EVP, Investments & GC | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2020 | 596,707 | 596,707 | - | - | LP interests in RPI US Partners 2019, LP | |
| George Lloyd | EVP, Investments & GC | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2020 | 83,638 | 83,638 | - | - | LP interests in RPI US Partners 2019, LP | |
| George Lloyd | EVP, Investments & GC | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2020 | 7,730 | 7,730 | - | - | LP interests in RPI US Partners 2019, LP | |
| George Lloyd | EVP, Investments & GC | 15 Jun 2020 | 262,760 | 273,960 | - | 0 | Class A Ordinary Shares | ||
| George Lloyd | EVP, Investments & GC | Purchase of securities on an exchange or from another person at price $ 28.00 per share. | 15 Jun 2020 | 11,200 | 11,200 | - | 28 | 313,600 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | Purchase of securities on an exchange or from another person at price $ 28.00 per share. | 15 Jun 2020 | 3,000 | 3,000 | - | 28 | 84,000 | Class A Ordinary Shares |
| George Lloyd | EVP, Investments & GC | 15 Jun 2020 | 26,276 | 2,050 | - | - | LP interests in RPI International Holdings 2019, LP | ||
| James Reddoch | EVP, Research & Investments | 15 Jun 2020 | 25,030 | 25,030 | - | 0 | Class A Ordinary Shares | ||
| James Reddoch | EVP, Research & Investments | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2020 | 29,117 | 29,117 | - | - | LP interests in RPI US Partners 2019, LP | |
| James Reddoch | EVP, Research & Investments | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2020 | 631,468 | 631,468 | - | - | LP interests in RPI US Partners 2019, LP | |
| James Reddoch | EVP, Research & Investments | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2020 | 2,698 | 2,698 | - | - | LP interests in RPI International Holdings 2019, LP | |
| James Reddoch | EVP, Research & Investments | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2020 | 200,000 | 200,000 | - | - | ICAI Interests | |
| James Reddoch | EVP, Research & Investments | 15 Jun 2020 | 2,503 | 195 | - | - | LP interests in RPI International Holdings 2019, LP | ||
| M. Germano Giuliani | Director, Ten Percent Owner | 15 Jun 2020 | 9,077,140 | 9,077,140 | - | 0 | Class A Ordinary Shares | ||
| M. Germano Giuliani | Director, Ten Percent Owner | 15 Jun 2020 | 3,477,520 | 3,477,520 | - | 0 | Class A Ordinary Shares | ||
| M. Germano Giuliani | Director, Ten Percent Owner | 15 Jun 2020 | 23,390,000 | 23,390,000 | - | 0 | Class A Ordinary Shares | ||
| M. Germano Giuliani | Director, Ten Percent Owner | 15 Jun 2020 | 22,926,170 | 22,926,170 | - | 0 | Class A Ordinary Shares | ||
| M. Germano Giuliani | Director, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 28.00 per share. | 15 Jun 2020 | 50,000 | 50,000 | - | 28 | 1,400,000 | Class A Ordinary Shares |
| M. Germano Giuliani | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2020 | 978,514 | 978,514 | - | - | LP interests in RPI International Holdings 2019, LP | |
| M. Germano Giuliani | Director, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Jun 2020 | 349,784 | 349,784 | - | - | LP interests in RPI International Holdings 2019, LP | |
| M. Germano Giuliani | Director, Ten Percent Owner | 15 Jun 2020 | 2,339,999 | 182,438 | - | - | LP interests in RPI International Holdings 2019, LP | ||
| M. Germano Giuliani | Director, Ten Percent Owner | 15 Jun 2020 | 2,292,617 | 178,821 | - | - | LP interests in RPI International Holdings 2019, LP | ||
| M. Germano Giuliani | Director, Ten Percent Owner | 15 Jun 2020 | 907,714 | 70,800 | - | - | LP interests in RPI International Holdings 2019, LP | ||
| M. Germano Giuliani | Director, Ten Percent Owner | 15 Jun 2020 | 347,752 | 2,032 | - | - | LP interests in RPI International Holdings 2019, LP |